Non-Coding RNA Profiles Of Dengue Virus 1-Infected Aedes albopictus Cells
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Date
2018-05
Authors
Azlan, Azali
Journal Title
Journal ISSN
Volume Title
Publisher
Universiti Sains Malaysia
Abstract
Aedes albopictus (Ae. albopictus), a competent vector of dengue virus
(DENV) and Chikungunya virus, is a highly invasive species . It is considered as a
public health threat throughout the world because of its high adaptability in both
tropical and temperate regions of the world, aggressive spread, and vector
competence (Chen et al., 2015). Despite being categorized as less efficient vector of
DENV than Aedes aegypti (Ae. aegypti), Ae. albopictus is the principal vector that
caused dengue epidemics (Cancrini et al., 2003). Therefore, comprehensive studies
on Ae. albopictus is important for understanding the mechanism underlying its
aggressive spread, high adaptability, and vector competence.
Numerous studies over the past several years have focused on Ae. aegypti,
primarily due to the availability of genome information (Nene et al., 2007). The
availability of genome sequence coupled with transcriptome data, facilitate the
process of studying this species in great details (Nene et al., 2007; Akbari et al.,
2013). Genetics and molecular studies done in Ae. albopictus are very limited due to
the lack of genome sequence and transcriptome. Recently, a complete genome
sequence and transcriptome data of Ae. albopictus have been released; thereby,
allowing extensive genetic and molecular analyses of this particular species (Chen et
al., 2015).
Description
Keywords
Aedes albopictus a competent vector of dengue virus , Chikungunya virus, is a highly invasive species