Comparison between 3D TOF magnetic resonance angiography and intra-arterial digital subtraction angiography in imaging the circle of willis
| dc.contributor.author | Mohd Ghazali, Rozita | |
| dc.date.accessioned | 2017-08-30T02:24:59Z | |
| dc.date.available | 2017-08-30T02:24:59Z | |
| dc.date.issued | 2002 | |
| dc.description.abstract | The purpose of this study is to compare the accuracy of 3D time of flight magnetic resonance angiography (3D TOF MRA) with intraarterial digital subtraction angiography (IADSA) in depicting the arterial segments of the circle of Willis. 38 patients who had underwent both 3D TOF MRA and IADSA examinations in Hospital Universiti Sains Malaysia from November 1998 to December 2000 were included in this study giving a total of 398 arterial segments compared and analysed. Two observers performed blinded retrospective analysis of the IADSA images and MIP display of the 3D TOF MRA of the circle of Willis on separate sessions. The AI, A2, Ml and PI segments were depicted as normal calibre, small or absent while the ACOM and PCOM segments were depicted as functional, patent or not visualised. The 3D TOF MRA was good in depiction of the Al, A2, Ml, Pl and ACOM segments of the circle of Willis with a sensitivity of 100%, 94.5%, 100%, 96.8% and 100% respectively. There were no false positive results for the Al, A2, Ml and PI segments with a positive predictive values of 100%. However, the positive predictive value for the ACOM segment was 89.5% (2 false positive results out of 19 segments). The specificity was excellent for the AI, A2 and PI segments at IOO% and acceptable for the ACOM segment at 90.5%. There were no false negative results for the AI and ACOM segments. However, the negative predictive value for the A2 and PI segments were low at 25% (3 out of 4 false negative results) and 60% (2 out of 5 false negative results) respectively. The 3D TOF MRA method was however a poor method for depiction of the PCOM segments with a sensitivity of 21.4%. The negative predictive value was very low at 5.2% with 53 out of 58 false negative results. Observer agreement between IADSA and 3D TOF MRA range from kappa "perfect" to ''slight" but inter-observer agreement for the 3D TOF MRA technique was excellent with the kappa values within the "perfect" range. MIP display of the 3D TOF MRA is sensitive for depicting the anatomy of the circle of Willis except for the PCOM segment. It is thus a reliable method for screening of this arterial circle. | en_US |
| dc.identifier.uri | http://hdl.handle.net/123456789/4456 | |
| dc.language.iso | en | en_US |
| dc.publisher | Universiti Sains Malaysia | en_US |
| dc.subject | 3D TOF magnetic resonance angiography (MRA) | en_US |
| dc.title | Comparison between 3D TOF magnetic resonance angiography and intra-arterial digital subtraction angiography in imaging the circle of willis | en_US |
| dc.type | Thesis | en_US |
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