An Immunohistochemical Study Of Survivin Expression In Normal And In Transformed Cells
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Date
2006-04
Authors
Alias, Iskandar Zulkarnain
Journal Title
Journal ISSN
Volume Title
Publisher
Universiti Sains Malaysia
Abstract
Survivin is a new member of the inhibitors of apoptosis protein (IAP) family, selectively
over-expressed in common human cancers but not in normal adult tissues. It is also
expressed in cancer cell lines. The study was performed generally to investigate the basic and clinical roles of survivin in normal and transformed cells. Rabbits were immunized with two synthetic oligopeptides, MGAPTLPPAWQP and KEFEETAKKVRRAIEQLAAMD amino acids sequences of the survivin molecule.
Description
Keywords
Immunohistochemical , Survivin Expression