EXPRESSION OF INTERLEUKIN 4, INTERLEUKIN 4 RECEPTOR AND IL-4 RECEPTOR RELATED GP200-MR6 MOLECULE IN PTERYGIUM AND NORMAL BULBAR CONJUNCTIVA TISSU
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Date
2001-11
Authors
Go, Eng Soon
Journal Title
Journal ISSN
Volume Title
Publisher
Pusat Pengajian Sains Perubatan Universiti Sains Malaysia
Abstract
IL-4 has been shown to have anti-tumoural activity in many cell lines. IL-4 needs to
bind with IL-4 Receptor to exert its action. Down-regulation of IL-4 associated gp200-
MR6 expression has been associated with increasingly malignant tissues.
Fifty-one pterygium and forty-one superior bulbar conjunctiva tissues from patients
with pterygium, along with fourteen conjunctiva samples from pterygium-free subjects
are subjected to immunohistochemical analysis to detennined the expression of IL-4,
IL-4 receptor and IL-4 receptor associated gp200-MR6 molecule.
Description
Keywords
MOLECULE IN PTERYGIUM , Ophthalmology