The Effects Of Combination Of Behavioural Intervention, Nutritional Education And Exercise (Combine) Program On Haemostatic Markers Among Obese Subjects
| dc.contributor.author | Omar, Norsuhana | |
| dc.date.accessioned | 2019-06-26T01:47:30Z | |
| dc.date.available | 2019-06-26T01:47:30Z | |
| dc.date.issued | 2012-06 | |
| dc.description.abstract | Obesity is a condition of excess body fat and it significantly increases the risk of coronary heart disease. Studies have shown that impaired haemostatic in obesity were found to predict future development of coronary heart disease and numbers of coronary events. The purpose of this study was to determine the effects of COMBINE program on the changes of anthropometry parameters, biochemical profile and haemostatic markers in obese subjects. The assessment was carried out on 28 obese subjects for 12-week duration. All subjects were required to give an informed consent before enrolling into the study. Anthropometric data were measured from the subjects selected before intervention (baseline) and after completing the program (post-intervention). About 15 ml of blood specimen was drawn from all subjects and tested for biochemical profile (e.g. fasting blood glucose and lipid profile) and haemostatic markers, such as fibrinogen, factor VII, thrombin activatable fibrinolytic inhibitors (TAFI), tissue plasminogen activators (t-PA), plasminogen activator inhibitors-1(PAI-1), plasminogen and Heparin Cofactor II at baseline and at post intervention. During this intervention period, the subjects were involved in a weekly program from 8.00 am until 1.00 pm on every Thursday at Hospital Universiti Sains Malaysia. The package of weight loss program consisted of brisk walking, dumb bell and easy-style of aerobic dance accompanied with nutrition education modules. Their food intake and physical activity were recorded in diary and they act as important tools in the behaviour modification method. Data analysis for this study was carried out using paired t-test, | en_US |
| dc.identifier.uri | http://hdl.handle.net/123456789/8390 | |
| dc.language.iso | en | en_US |
| dc.publisher | Universiti Sains Malaysia | en_US |
| dc.subject | Obesity is a condition of excess body fat | en_US |
| dc.subject | increases the risk of coronary heart disease | en_US |
| dc.title | The Effects Of Combination Of Behavioural Intervention, Nutritional Education And Exercise (Combine) Program On Haemostatic Markers Among Obese Subjects | en_US |
| dc.type | Thesis | en_US |
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