Evaluation Of Type-2 Diabetes Mellitus Among Hepatitis B And C Patients In Penang General Hospital, Malaysia

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dc.contributor.authorHamoodi, Hani Kareem
dc.date.accessioned2018-07-30T02:11:13Z
dc.date.available2018-07-30T02:11:13Z
dc.date.issued2011-07
dc.description.abstractDiabetes mellitus (DM) and chronic hepatitis C (HCV) and B (HBV) virus infections are relatively common disorders and considered as worldwide, major public health problems with increasing complication and mortality rates. An epidemiologic link between chronic hepatitis virus infection and diabetes mellitus has recently been reported. Many of previous studies have revealed a higher prevalence of DM in patients with HCV-related chronic liver disease when compared to patients with chronic liver disease resulting from other etiologies. Many other studies have reported similar relationship between diabetes and hepatitis B virus infection but with lower frequencies. The aims of this study are to evaluate the occurrence of type-2 diabetes among patients with chronic hepatitis B or C virus infections and to investigate the risk factors which are associated with the development of type-2 diabetes in hepatitis population. A retrospective cross-sectional study was conducted in Penang General Hospital, Penang, Malaysia. A total of 520 patients with hepatitis B and C were enrolled in this study according to the inclusion criteria of the study. Among 520 patients, 269 were diagnosed with chronic hepatitis B and 251 with chronic hepatitis C infection. The patients’ records were reviewed to select the required data for the study such as the presence of type-2 diabetes, type of chronic viral hepatitis, laboratory data, demographic data and clinical outcomes. This study included 331 males and 189 females. Out of those, 177 patients are Malay, 319 Chinese and 24 Indian. There was a significant association between chronic hepatitis infection type-2 diabetes, in which, the prevalence of diabetes was significantly higher in hepatitis C (25.9%) than in hepatitis B (16.4%) infection (p = 0.008). After adjusting the confounding variables by applying logistic regression, diabetes occurrence was associated with race (OR = 3.16, 95% CI = 1.90-5.24, p value = 0.001), age group (OR = 2.53, 95% CI = 1.41-15.45, p value = 0.002), family history of diabetes (OR = 3.51, 95% CI = 1.73-7.10, p = 0.001) and type of hepatitis (OR = 1.70, 95% CI = 1.07-2.70, p value = 0.023).en_US
dc.identifier.urihttp://hdl.handle.net/123456789/6062
dc.language.isoenen_US
dc.publisherUniversiti Sains Malaysiaen_US
dc.subjectDiabetes mellitus and chronic hepatitis C and Ben_US
dc.subjectcommon disorders and considered as worldwideen_US
dc.titleEvaluation Of Type-2 Diabetes Mellitus Among Hepatitis B And C Patients In Penang General Hospital, Malaysiaen_US
dc.typeThesisen_US
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