Prevalence of eosinophilic nasal polyps and analysis of their presentation in HUSM Kubang Kerian, Kelantan
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Date
2011-05
Authors
Yahia, F. Hussein
Journal Title
Journal ISSN
Volume Title
Publisher
Pusat Pengajian Sains Perubatan Universiti Sains Malaysia
Abstract
Nasal polyp pathogeneses and etiology is still unknown, but now it is regarded as one form of the chronic inflammatory reaction of the sinonasal mucosa which eosinophiles are mainly involved in the mechanism of its formation. It is quite common disease affecting 1-2 % of the adult population and has the potential for high recurrence. Clinically most of the patients are complaining of nasal blockage and reduce sense of smell. The easy accessibility to the nasal polyp facilitates histological examination of it and broadly divided them into two histological subtypes the eosinophilic and non-eosinophilic types. The aim of the study was to determine the
percentage of each histological subtype of the nasal polyp and to study the association of the clinical presentation of each type. Sixty two patients with nasal polyp underwent functional endoscopic sinus surgery (FESS) in HUSM over the period of four years extending from 2004 to 2008 were included in the study and their histopathological reports were reviewed and their clinical presentation was studied in relation to the symptoms and the findings were written in specifically prepared form for this purpose.Eighty seven percent of the sample had eosinophilic type of nasal polyp and thirteen percent had non-eosinophilic.There was no statistically significant difference in the clinical presentation in relation to nasal blockage or loss of smell
between the two histological subtypes. High recurrence rates was noted among our subjects compared to published figures for the same surgical intervention (FESS). The study showed that the incidence of histological subtypes of nasal polyp is almost the same as that found in other parts of the world (Europe and North America) which will reduce the possibility of racial or geographical influence on the pathogenesis of the nasal polyp.Clinical symptoms and presentation alone are not enough to differentiate the type of the nasal polyp without the histological studies.
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Keywords
Otorhinolaryngology , Head and Neck Surgery