Understanding The Molecular Enteropathogenesis Of Martx Toxin Genes And Cholera Toxin Gene Mutations Of Vibrio Cholerae O139 Serogroup Towards Cholera Vaccine Development

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dc.contributor.authorTan, Gim Cheong
dc.date.accessioned2018-09-20T06:53:39Z
dc.date.available2018-09-20T06:53:39Z
dc.date.issued2010
dc.description.abstractCholera is a lethal diarrheal disease caused by toxigenic V. cholerae of O1 and O139 serogroups. Early diagnosis and prompt treatments of the disease are needed to prevent death in these patients. Even though the spreading of the disease could be controlled with proper sanitation, the best way to prevent cholera is through vaccination. There are several cholera vaccines available for O1 serogroup V. cholerae but they do not cross-protect against O139 serogroup. The bivalent O1/O139 cholera vaccine also did not show satisfactory protective immune response against O139 serogroup in clinical trials.en_US
dc.identifier.urihttp://hdl.handle.net/123456789/6599
dc.language.isoenen_US
dc.publisherUniversiti Sains Malaysiaen_US
dc.subjectMolecular Enteropathogenesis Of Martx Toxin Genes And Cholera Toxin Gene Mutationsen_US
dc.subjectVibrio Cholerae O139 Serogroup Towards Cholera Vaccineen_US
dc.titleUnderstanding The Molecular Enteropathogenesis Of Martx Toxin Genes And Cholera Toxin Gene Mutations Of Vibrio Cholerae O139 Serogroup Towards Cholera Vaccine Developmenten_US
dc.typeThesisen_US
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