The expression of ppars gamma in the cervical cancer line, bela and the effects of specific PPAR ligand on cell growth
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Date
2013
Authors
Nik Soriani, Yaacob
Journal Title
Journal ISSN
Volume Title
Publisher
Pusat Pengajian Sains Perubatan
Abstract
To quantify the mRNA expression levels of PPARy in the cervical cancer cell line, HeLa, using real-time PCR. To correlate the findings in (1) with the corresponding protein expression levels by Western blotting. To correlate the transcriptional and translational levels of PPARy with markers of apoptosis in these cells. To determine whether addition of specific PPARy ligands to the tumour cell line would modulate the above parameters.
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Keywords
Genetics and molecular biology