Comparative Evaluation Of Analgesic, Antioxidant And Antimicrobial Activities Of Five Selected Medicinal Plants
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Date
2014-02
Authors
Venkatappa, Annegowda Hardur
Journal Title
Journal ISSN
Volume Title
Publisher
Universiti Sains Malaysia
Abstract
Plants with medicinal values are known to possess bioactive compounds and
contributed greatly to the existence of several currently available pharmaceuticals. In
view of this the present study was conducted to evaluate the antioxidant,
antinociceptive and antimicrobial activities of traditionally used local plants like
Terminalia catappa, Piper betle, Bauhinia purpurea, Cinnamomum iners and
Callicarpa furfuracea. In this study sonication, maceration and soxhlet extraction
techniques were used to obtain their respective plant extracts. The in vitro
antioxidant, antimicrobial activity and polyphenolic content determination revealed
the presence of significant biological activities and phenolic content in the extract
obtained by sonication followed by maceration and soxhlet extraction.
Among the plant extracts studied for antioxidant activity, T. catappa extract
showed remarkable antioxidant activity followed by P. betle, B. purpurea, C. iners
and C. furfuracea extracts. The antioxidant activity displayed by T. catappa extract
was significantly higher than commercially available grape seed extract and synthetic
antioxidant butylated hydroxytoluene. In addition, T. catappa extract also revealed
marked antimicrobial activity against both Gram-positive and Gram-negative
bacterial strains followed by B. purpurea, P. betle and C. iners. Soxhlet ethanolic
extract of C. furfuracea leaf, stem and root possessed least polyphenolic content,
antioxidant and antimicrobial activities when compared with other plant extracts.
This is the first ever study regarding the biological investigations of C. furfuracea.
Description
Keywords
Analgesic, Antioxidant , Selected Medicinal Plants