Parameters Predicting Clinical Sepsis In Neonates
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Date
2015-12
Authors
Ahlam Abulqasem, Aldelimi
Journal Title
Journal ISSN
Volume Title
Publisher
Universiti Sains Malaysia
Abstract
Introduction:
Neonatal sepsis is a major health problem worldwide. The definition of sepsis remains an extremely difficult issue. This study aimed to determine the most useful parameters to predict confirmed sepsis or clinical sepsis.
Methods:
This was a cross sectional study conducted in NICUs at Hospital USM and HRPZ II between July 2012 and July 2013 involving all newborns who were started on antibiotics. A special sticker and the folders of enrolled neonates were reviewed for each episode of suspected infection.
Based on blood culture results and duration of antibiotics, babies were divided into: confirmed sepsis, clinical sepsis and no sepsis. Thirty four sepsis related parameters were checked for their association with positive blood cultures in each group using Chi-square and Fisher’s exact tests. The sensitivity and specificity of individual parameters were determined using 2x2 tables and for the predictive model were determined using Stata software.
Description
Keywords
Parameters Predicting , Clinical Sepsis In Neonates