Preparation and characterization of collagen grafted poly(dimethyl siloxane) modified films for skin substitute applications.

dc.contributor.authorDarvishi, Seyed Mahmood Rezaei
dc.date.accessioned2018-11-07T03:45:12Z
dc.date.available2018-11-07T03:45:12Z
dc.date.issued2011-02
dc.description.abstractPoli(dimetil siloxana) (PDMS) filem yang berpusat diubah dengan menggunakan hidrogel dan kolagen untuk menghasilkan pelbagai jenis pengganti kulit. PHEMA (poli(hidroksietil metakrilat)) dan PAA (poli(asid akrilik)) digunakan melalui kaedah jujukan IPN (interpenetrating polymer networks) dan kaedah campuran bagi menghasilkan suatu kumpulan fungsi yang sesuai untuk menempatkan kologen pada lapisan luar PDMS, dalam usaha meningkatkan kebioserasian mereka. Poly(dimethyl siloxane) (PDMS) based films were modified using hydrogels and collagen to produce different types of skin substitute. Poly(hydroxyethyl methacrylate) (PHEMA) and poly(acrylic acid)(PAA) were used via sequential method of interpenetrating polymer networks (IPNs) and blending methods to create suitable functional groups to immobilize collagen in outer layer of PDMS in order to enhance their biocompatibility.en_US
dc.identifier.urihttp://hdl.handle.net/123456789/7005
dc.language.isoenen_US
dc.publisherUniversiti Sains Malaysiaen_US
dc.subjectCollagenen_US
dc.subjectSkin substituteen_US
dc.titlePreparation and characterization of collagen grafted poly(dimethyl siloxane) modified films for skin substitute applications.en_US
dc.typeThesisen_US
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