COMPARISON OF ANXIETY AND DEPRESSION BETWEEN PATIENT WITH AND WITHOUT FIXED AIRFLOW LIMITATION IN SEVERE ASTHMATICS IN HOSPITAL UNIVERSITI SAINS MALAYSIA AND HOSPITAL RAJA PEREMPUAN ZAINAB II
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Date
2011
Authors
WAN HASMAWATI, WAN ISMAIL
Journal Title
Journal ISSN
Volume Title
Publisher
Pusat Pengajian Sains Perubatan Universiti Sains Malaysia
Abstract
Introduction: Asthma is a common chronic disease worldwide. Despite important
advances in diagnosis and treatment, asthma has become a public health problem for all
countries. Poorly controlled asthma exerts a high cost for both patients and society. Fixed
airflow limitation can develop in patients with severe asthma. Anxiety and depression
were significantly more common among asthmatic patients and psychiatric co-morbidity
is associated with poor asthma outcome.
Objective: To compare the prevalence of anxiety and depression between patients with
and without fixed airflow limitation among severe asthmatic patients and to determine the
association between anxiety and depression with airflow limitation in severe asthmatic
patients
Methodology: This was a comparative cross sectional study among 158 severe asthmatic
patients attending the Chest clinic follow-up in Klinik Pakar Perubatan HUSM and HRPZ
II from 15 August 2009 till 15 April 2010. Each patient was interviewed and their
medical notes were reviewed to assess their medications as well as their asthma severity.
Spirometry test was performed to determine the presence of fixed airflow limitation.
They were then given two sets of self- administer questionnaires; i) the sociodemographic
questionnaire and ii) the Malay HADS questionnaire.
Result: There were 81 patients in the fixed airflow limitation group with mean age (sd)
of 54.1(9.8) and 77 patients in the group without fixed airflow limitation with mean age
of 50.1(12.3). The prevalence of anxiety and depression in the fixed airflow limitation
group was both 29.6% whereas in the group without fixed airflow limitation were 24.7%
and 18.2% respectively. Simple and multiple logistic regressions found no significant
relationship between anxiety or depression and presence of fixed airflow limitation.
Conclusion: The prevalence of anxiety and depression in severe asthmatic patients with
fixed airflow limitations is similar to those without fixed airflow limitation. There is no
increased risk of developing anxiety or depression associated with having fixed airflow
limitation in severe asthmatics.
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Keywords
Family Medicine