Antimicrobial, Anticancer And Antioxidant Activities Of Methanolic Extract Of Elaeis Guineensis Jacq. Leaves
| dc.contributor.author | Soundararajan, Vijayarathna | |
| dc.date.accessioned | 2019-06-28T01:02:23Z | |
| dc.date.available | 2019-06-28T01:02:23Z | |
| dc.date.issued | 2012-06 | |
| dc.description.abstract | Malaysia, being one of the economically industrious producers of oil palm around the world correspondingly, had recognized for its assiduous and phenomenal expansion of oil palm (Elaeis guineensis) plantings. Though the plantation had considerably contributed to the nation, the by-products yielded during replanting, harvesting and pruning became controvertible. There are several by-products of oil palm, explicitly oil palm fronds (OPF) had been contributing 70% to the overall oil palm industry waste in the country which reportedly produced around 30 million tons annually of oil palm biomass, including trunks, fronds, and empty fruit bunches. One of the significant problems in palm fruit processing is managing the wastes generated during the process. Hence, this study was executed to transmute oil palm industrial waste into remedial pharmaceutical products to which activities such as antimicrobial, anticancer, antioxidant and cytotoxicity were evaluated. The antimicrobial activity of the extract was completed using disc diffusion method and minimum inhibitory concentration (MIC) assay per broth macrodilution method. The extract was found to be potent towards the tested microorganism with the MIC reading between 6.25- 50.00 mg/mL. It was found that the extract works effectively against pathogenic yeast, C. albican, under the MIC value of 6.25 mg/mL and this result was again reinstated through time killing assay. Scanning Electron Microscopy (SEM) and Transmission Electron Microscopy (TEM) were conducted to observe the morphological metamorphosis between extract treated C. albicans and untreated control cells. The visual image results of SEM and TEM further testify the significant effects of the extract against the cell wall and the cytoplasmic contents of C. albicans cells eventuating in the destruction of cells that are exposed to the concentration of 6.25 mg/mL E. guineensis extract throughout 36 hours. | en_US |
| dc.identifier.uri | http://hdl.handle.net/123456789/8428 | |
| dc.language.iso | en | en_US |
| dc.publisher | Universiti Sains Malaysia | en_US |
| dc.subject | Antimicrobial, anticancer and antioxidant activities of | en_US |
| dc.subject | methanolic extract of Elaeis guineensis Jacq. leaves | en_US |
| dc.title | Antimicrobial, Anticancer And Antioxidant Activities Of Methanolic Extract Of Elaeis Guineensis Jacq. Leaves | en_US |
| dc.type | Thesis | en_US |
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