A preliminary study of ultrasonographic appearances of gall bladder and biliary tract in clinically suspected biliary atresia
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Date
2006
Authors
Yusoff, Wan Norhayati Wan
Journal Title
Journal ISSN
Volume Title
Publisher
Pusat Pengajian Sains Perubatan, Universiti Sains Malaysia
Abstract
Topic : A Preliminary Study of the Ultrasonographic Appearances of Gall
Bladder and Biliary Tract in Clinically Suspected Biliary Atresia.
Background : Biliary atresia is one of the congenital anomalies that has high
mortality rate which is characterized by a fibrosclerosing obliteration of the
extrahepatic duct that uniquely presents in the first months of life. It is also the
most frequent cause of chronic end-stage liver disease in children and
accounting for 40 to 50 % of all pediatric liver transplants. Ultrasonography has
been one of the diagnostic workouts, where early and specific diagnostic tools
are important in achieving the correct diagnosis for better prognosis of patients.
Methods and Materials : This is a retrospective cross sectional study, involving
32 clinically suspected biliary atresia infants with 32 normal infants as a control
group. The aim of this study is to compare the gall bladder appearance and it
measurements between disease and control group. Triangular cord was
assessed in the porta hepatis from hepatobiliary ultrasonography done from
January 2003 till December 2005 in HUSM between clinically suspected biliary
atresia infants and normal control group.
Results : Most of the infants were term infants with normal birth weight. There
was no significant difference noted between sex, race, gestational age and day
of ultrasound performed between the clinically suspected biliary atresia andnormal control subject. Significant difference was noted between the gall bladder
wall thickness, length and width between the two group with p value of 0.009,
0.001 and 0.022 respectively.
Conclusion : There is a significant difference noted in the gall bladder length,
width and wall thickness between the clinically suspected biliary atresia and
normal control group. Gall bladder was present in 84.4 % of cases and triangular
cord sign was present in 20.1 % in clinically suspected biliary atresia infants.
Description
Keywords
Biliary tract