Pressure modulation of Ficus deltoidea and Orthosiphon stamineus leaves extracts in spontaneously hypertensive rats.
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Date
2015
Authors
Dewa, Aidiahmad
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Abstract
in-vitro studies using aortic rings of spontaneusly hypertensive rats (SHRs) have shown that extracts of both Ficus deltoidea (FD) and Orthosiphon stamineus 8enth. (OS) are potentially able to regulate blood pressure to a lower level at the peripheral level involving pathways of endothelium-derived nitric oxide (EDNa), cyclic GMP and prostacyclin. in-vivo studies of the vascular reactivity of the selected FD and as extracts using both approaches, non pithed and pithed treated hypertensive rats, supported the potential of the extracts of their anti-hypertensive potential. The methanolic extract of FD and water extract of OS found to be the most potential in moderating high blood pressure in hypertension.
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Keywords
Ficus deltoidea , Orthosiphon stamineus , hypertensive rats