Geometric morphometric analysis of dental cast and cephalometries of Malays cleft lip and palate

dc.contributor.authorM. Alomari, Amjad
dc.date.accessioned2015-07-30T04:36:09Z
dc.date.available2015-07-30T04:36:09Z
dc.date.issued2009
dc.description.abstractCleft lip and palate (CLP) is the most common congenital oro-facial deformity. Patients with CLP may have difficulty in feeding, middle ear infection as well as psychological problems. Management of CLP requires interventions from multiple disciplines which start from the first day of life and continue up to the adulthood. Moreover, the development of CLP patients does not follow usual developmental growth after con·ective surgeries. In this study, we aim to document the morphological differences of Malay children between non-cleft (NC) and CLP, in term of size, shape and directionality changes applying geometric morphometries method. This study includes 6-12 years old children, with average age 9.5 ± 1.3 years. They were divided into three groups; non-cleft (NC), unilateral cleft lip and palate (UCLP), bilateral cleft lip and palate (BCLP). Ninety three dental casts and lateral cephalometries were collected. Twenty four homologous landmarks were digitized on upper and lower dental cast and eleven homologous landmarks on lateral cephalometric. The mean of compared groups were subjected to finite element analysis (FEA) using MorphoStudio™ software to demonstrate the sources of heterogeneity in the CLP in term of size changes, shape changes and directionality of shape changes. In this study, NC group showed significant differences from CLP group. Upper dental arch and maxillary complex showed high morphological differences than lower dental arch and mandible, as cleft affect growth of this area. In comparison of UCLP and BCLP, they were comparable in result except intercanine width was more constricted in BCLP. Moreover, maxillary length was longer in BCLP compared to UCLP. For shape changes, upper dental arch and maxillary complex showed significant changes than lower dental arch and mandible, while directionality changes of compared groups were non-homogenous. The difference in morphology of CLP versus NC in this study could contribute important information to clinician treating the patients.en_US
dc.identifier.urihttp://hdl.handle.net/123456789/1009
dc.subjectCephalometriesen_US
dc.subjectMalays cleft lipen_US
dc.titleGeometric morphometric analysis of dental cast and cephalometries of Malays cleft lip and palateen_US
dc.typeThesisen_US
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