The relationship between protein and mrna expression of transcription repressor dream, c-fos and prodynorphin in modulating pain responses induced by formalin in the rat spinal cord.

dc.contributor.authorLong, Idris
dc.date.accessioned2018-10-19T08:16:59Z
dc.date.available2018-10-19T08:16:59Z
dc.date.issued2011-07
dc.description.abstractProtein Downstream Regulatory Element Antagonist Modulator (DREAM) bertindak sebagai penindas transkripsi bagi gen c-Fos dan prodynorphin yang terlibat dalam proses kesakitan. Kajian ini dijalankan untuk mengesan perkaitan di antara ekspresi protein dan mRNA bagi DREAM, c-Fos dan prodynorphin di dalam meminda tindak balas kesakitan yang dicetuskan oleh formalin melalui reseptor opioid dan bukan-opioid dalam korda spina tikus. Downstream Regulatory Element Antagonist Modulator (DREAM) protein acts as a transcription repressor for c-Fos and prodynorphin gene which is involved in modulating pain processes. This study was conducted to investigate the relationship between DREAM, c-Fos, prodynorphin protein and mRNA expression through opioid and non-opioid receptors in the modulation of pain responses induced by formalin in the rat spinal cord.en_US
dc.identifier.urihttp://hdl.handle.net/123456789/6824
dc.language.isoenen_US
dc.publisherUniversiti Sains Malaysiaen_US
dc.subjectProteinen_US
dc.subjectModulatingen_US
dc.titleThe relationship between protein and mrna expression of transcription repressor dream, c-fos and prodynorphin in modulating pain responses induced by formalin in the rat spinal cord.en_US
dc.typeThesisen_US
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