The relationship between protein and mrna expression of transcription repressor dream, c-fos and prodynorphin in modulating pain responses induced by formalin in the rat spinal cord.
dc.contributor.author | Long, Idris | |
dc.date.accessioned | 2018-10-19T08:16:59Z | |
dc.date.available | 2018-10-19T08:16:59Z | |
dc.date.issued | 2011-07 | |
dc.description.abstract | Protein Downstream Regulatory Element Antagonist Modulator (DREAM) bertindak sebagai penindas transkripsi bagi gen c-Fos dan prodynorphin yang terlibat dalam proses kesakitan. Kajian ini dijalankan untuk mengesan perkaitan di antara ekspresi protein dan mRNA bagi DREAM, c-Fos dan prodynorphin di dalam meminda tindak balas kesakitan yang dicetuskan oleh formalin melalui reseptor opioid dan bukan-opioid dalam korda spina tikus. Downstream Regulatory Element Antagonist Modulator (DREAM) protein acts as a transcription repressor for c-Fos and prodynorphin gene which is involved in modulating pain processes. This study was conducted to investigate the relationship between DREAM, c-Fos, prodynorphin protein and mRNA expression through opioid and non-opioid receptors in the modulation of pain responses induced by formalin in the rat spinal cord. | en_US |
dc.identifier.uri | http://hdl.handle.net/123456789/6824 | |
dc.language.iso | en | en_US |
dc.publisher | Universiti Sains Malaysia | en_US |
dc.subject | Protein | en_US |
dc.subject | Modulating | en_US |
dc.title | The relationship between protein and mrna expression of transcription repressor dream, c-fos and prodynorphin in modulating pain responses induced by formalin in the rat spinal cord. | en_US |
dc.type | Thesis | en_US |
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