Molecular cloning and functional Characterization of blue-spotted mudskipper (boleophthalmus boddarti) Fatty acyl desaturase and elongase.
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Date
2016-09
Authors
Han Jie, Soo
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Publisher
Universiti Sains Malaysia
Abstract
Asid lemak tak tepu yang berantai panjang (LC-PUFA) membawa banyak manfaat kepada manusia dan amat penting untuk fungsi tubuh dari aspek fisiologi dan pertumbuhan. Berbanding dengan desaturase (Fads) dan elongase (Elovl) mammalia berfungsi terhadap substrat yang terhad, Fads dan Elovl dalam ikan teleost mempamerkan aktiviti terhadap pelbagai substrat yang diakibatkan perbezaan sumber LC-PUFA di dalam habitat ikan.
Long chain polyunsaturated fatty acids (LC-PUFAs) serve many important roles in human are important for physiological and developmental well being. Unlike mammalian desaturases (Fads) and elongases (Elovl) that have tight selections of fatty acid substrates, the desaturase and elongase in teleost displayed much diversified functionality and this was hypothesized to be driven mainly by PUFA abundance in diet and their respective habitat.
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Keywords
Molecular , Cloning