DEMONSTRASI KEHADIRAN PROTEIN PERMUKAAN SEL YANG ANTIGENIK DAN SPESIFIK UNTUK Shigella spp. DAN PEMBANGUNAN KE ARAH UJIAN DIAGNOSTIK SEGERA BAGI PENYAKIT SHIGELOSIS
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Date
2001-01
Authors
KIRNPAL KAUR, BANGA SINGH
Journal Title
Journal ISSN
Volume Title
Publisher
Pusat Pengajian Sains Perubatan Universiti Sains Malaysia
Abstract
Shigella spp. is the major etiologic agent of dysentery or bloody diarrhoea in
humans. It has been identified as an important cause for morbidity and mortality
among children especially in developing countries. Early diagnosis of shigellosis
is the major strategy for limiting this highly contagious disease. Since routine
culturing and bacterial determination from patients' faeces are laborious, timeconsuming,
relatively expensive and of low sensitivity, the development of a
more rapid and simplified diagnostic test for shigellosis is highly desirable. The
test must be sensitive, specific, easy to perform, cost-effective and be able to
detect the presence of Shigella spp. directly from patients' specimen especially
faeces. As such, the objective of this study was to determine the presence of a
specific and antigeniC protein for Shigella spp. and to use it for the development
of a rapid diagnostic test for shigellosis.
Description
Keywords
Shigella spp