A Qualitative Study On Barriers And Facilitators And Strategies To Improve Adherence To Antidepressants Among Outpatients With Major Depressive Disorder
| dc.contributor.author | Ho, Siew Ching | |
| dc.date.accessioned | 2019-08-05T01:41:39Z | |
| dc.date.available | 2019-08-05T01:41:39Z | |
| dc.date.issued | 2017-01 | |
| dc.description.abstract | Major depressive disorder (MDD) is associated with a high rate of relapse and recurrence. One of the major challenges in treating MDD is patients’ nonadherence to medication. The objectives aimed: (1) to explore the barriers and facilitators of patients’ adherence to antidepressants among outpatients with MDD; (2) to identify strategies that aimed to improve adherence from the perspective of various stakeholders. A qualitative study using semi-structured and individual indepth interviews was conducted in phase I of the study. Thirty participants were purposively sampled from different ethnicities to achieve maximum variation in sampling, and data were collected until it reached thematic saturation. Interviews were conducted using a validated topic guide and responses were audio-tape recorded, transcribed verbatim, checked, and analysed using the grounded theory approach. In phase II, a Delphi survey involving 20 panellists from physicians, pharmacists, and nurses/medical assistant; was conducted to validate a list of strategies that aimed to improve patients’ adherence. Panellists completed tworounds of self-administered questionnaires to obtain a group consensus for the strategies identified. Results from phase I showed that 40 different themes and subthemes were identified which were conceptually divided into two distinct categories related to barriers and facilitators to adherence. The barriers were: patient-specific barriers (sub-categorised into erroneous beliefs, forgetfulness, negative attitudes, and lack of knowledge), medication-specific barriers (side effects, pill burden, treatment duration, and costs), healthcare provision and system, social-cultural barriers (lack of support, barriers related to religion and cultural beliefs, and stigma), and logistic barriers. | en_US |
| dc.identifier.uri | http://hdl.handle.net/123456789/8562 | |
| dc.language.iso | en | en_US |
| dc.publisher | Universiti Sains Malaysia | en_US |
| dc.subject | Barriers and facilitators and strategies to improve adherence | en_US |
| dc.subject | antidepressants among outpatients with major depressive disorder | en_US |
| dc.title | A Qualitative Study On Barriers And Facilitators And Strategies To Improve Adherence To Antidepressants Among Outpatients With Major Depressive Disorder | en_US |
| dc.type | Thesis | en_US |
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