In vitro cytotoxicity evaluation of locally produced dental porcelain

dc.contributor.author	Husein, Adam
dc.date.accessioned	2021-07-13T03:11:08Z
dc.date.available	2021-07-13T03:11:08Z
dc.date.issued	2011
dc.description.abstract	The in vitro cytotoxic potential of locally produced dental porcelain was evaluated in this study. The cellular response of human osteoblast and MRC-5 cell lines were assessed using MTT assay by incubatiog with the fluid extract of dental porcelain powder and dental porcelain discs (direct test). Aging process was carried out by submerging the discs into 3% Bovine Serum Albumin (BSA) solution. Tests on extracts showed that the material was significantly different from the control at a concentration of 250 mg/ml. Direct test showed thRt the material after aging was not significantly different from the control with a mean (SD) of 89.2(13.4) %, whereas, it was significantly different from the control before conditioning of BSA with a mean (SD) of 88.5(12.1) %. However, the dental porcelain caused mild suppression of succinate dehydrogenase activity (<25%), which is considered to be accepted clinically and hence can be ranked as being non-cytotoxic or mildly cytotoxic.	en_US
dc.identifier.uri	http://hdl.handle.net/123456789/13713
dc.language.iso	en	en_US
dc.publisher	Pusat Pengajian Sains Pergigian, Universiti Sains Malaysia	en_US
dc.subject	porcelain	en_US
dc.title	In vitro cytotoxicity evaluation of locally produced dental porcelain	en_US
dc.type	Other	en_US

Now showing 1 - 1 of 1