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Computational Design And Investigation Of New Benzophenones And Benzophenone Imines Inhibitors For Breast Cancer

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dc.contributor.authorShtaiwi, Amneh Mohammad
dc.date.accessioned2025-09-24T02:22:19Z
dc.date.available2025-09-24T02:22:19Z
dc.date.issued2018-10
dc.description.abstractThe computational methods of protein-ligand interactions are core components in drug design and modem drug discovery. This study attempted to design and investigate the interactions of new human estrogen receptor (hERa) inhibitors to treat breast cancer cells using molecular modeling approach. The proposed inhibitors were designed by replacing the triarylethylene estrogenic scaffold found in the synthetic inhibitor 4-hydroxytamoxifen (4-0HT) with triarylimine Schiff bases.
dc.identifier.urihttps://erepo.usm.my/handle/123456789/22622
dc.language.isoen
dc.subjectBenzophenone
dc.subjectImines
dc.titleComputational Design And Investigation Of New Benzophenones And Benzophenone Imines Inhibitors For Breast Cancer
dc.typeResource Types::text::thesis::doctoral thesis
dspace.entity.typePublication
oairecerif.author.affiliationUniversiti Sains Malaysia
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