Single-stage biosynthesis of poly(3-hydroxybutyrate-co-4-hydroxybutyrate) using Cupriavidus sp. USMAA1020 via mixed-substrate cultivation strategy.

dc.contributor.authorKai Hee, Huong
dc.date.accessioned2018-10-05T01:58:26Z
dc.date.available2018-10-05T01:58:26Z
dc.date.issued2017-03
dc.description.abstractKopolimer poli(3-hidroksibutirat-ko-4-hidroksibutirat) [P(3HB-ko-4HB)] merupakan polihidroksialkanoat (PHA) yang penting dalam bidang biofarmaseutikal dan perubatan. Produktiviti kopolimer dengan komposisi 4HB yang tinggi sering dicapai melalui pengkulturan dua-peringkat tetapi ini menyukarkan dengan meningkatkan masa dan usaha pengendalian, dan risiko kontaminasi dalam proses penghasilan berskala besar. Poly(3-hydroxybutyrate-co-4-hydroxybutyrate) [P(3HB-co-4HB)] copolymer is polyhydroxyalkanoate (PHA) with biopharmaceutical and medical significance. Copolymer productivity with high 4HB monomer composition is usually achieved via two-stage cultivation but this reduces the ease of handling by increasing the time, effort and risk of contamination in large-scale production.en_US
dc.identifier.urihttp://hdl.handle.net/123456789/6672
dc.language.isoenen_US
dc.publisherUniversiti Sains Malaysiaen_US
dc.subjectBiosynthesisen_US
dc.subjectCultivation strategyen_US
dc.titleSingle-stage biosynthesis of poly(3-hydroxybutyrate-co-4-hydroxybutyrate) using Cupriavidus sp. USMAA1020 via mixed-substrate cultivation strategy.en_US
dc.typeThesisen_US
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