Asymmetric Synthesis Of Cardiovascular Drug Precursor (L-Homophenylalanine) Via Integrated Enzymatic Membrane Bioreactor

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dc.contributor.authorOh, Pei Ching
dc.date.accessioned2018-11-30T02:25:57Z
dc.date.available2018-11-30T02:25:57Z
dc.date.issued2011-12
dc.description.abstractOver the past decade, L-homophenylalanine (L-HPA) is extensively used in the pharmaceutical industry, as a precursor for production of angiotensin-converting enzyme (ACE) inhibitor. which processes significant clinical application in the management of hypertension and congestive heart failure (CHF). A number of chemical methods have been reported thus far for the synthesis of L-HPA. However, chemical methods generally suffer from process complexity, high cost, and environmental pollution. On the other hand, enantiomerically pure L-HPA can be synthesized elegantly and efficiently by employing biocatalytic methods. Where it appears to be the most attractive process in terms of potential industrial applications, green chemistry and sustainability.en_US
dc.identifier.urihttp://hdl.handle.net/123456789/7167
dc.language.isoenen_US
dc.publisherUniversiti Sains Malaysiaen_US
dc.subjectSynthesis of cardiovascular drug precursoren_US
dc.subjectvia integrated enzymatic membrane bioreactoren_US
dc.titleAsymmetric Synthesis Of Cardiovascular Drug Precursor (L-Homophenylalanine) Via Integrated Enzymatic Membrane Bioreactoren_US
dc.typeThesisen_US
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