Assessment Of Chemotherapy Outcome And Adverse Event Management Among Solid Cancer Patients Of Penang Hospital

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dc.contributor.authorHassan, Bassam Abdul Rasool
dc.date.accessioned2019-01-29T02:35:38Z
dc.date.available2019-01-29T02:35:38Z
dc.date.issued2013-05
dc.description.abstractDuring this century, cancer has become one of the major problem and diseases which has caused predominant death and will even surpass heart diseases. Both cancer diseases and chemotherapy have many hazardous side effects which could also affect the quality of life (QOL) of cancer patients. Thus this study was performed to detect the main risk factors associated with nausea and vomiting, anemia, thrombocytopenia and hypercalcemia and to evaluate effectiveness of respective treatment guidelines. In addition QOL of breast cancer patients with nausea and vomiting was also evaluated. Prospective and retrospective studies were conducted on solid cancer patients admitted to Penang, Hospital. Data were collected by using direct person-toperson interview for the prospective part (nausea and vomiting) and by using specific data sheet for the retrospective part (anemia, thrombocytopenia and hypercalcemia). The required data were collected from patients’ files kept in the oncology clinic and the record office of the hospital. The prospective study focused on risk factors and QOL of breast cancer patients (n=158) suffering from nausea and vomiting after chemotherapy administration. These risk factors include patient's demographic data, breast cancer information, chemotherapy data, patients’ characteristic data and treatment of nausea and vomiting. The main risk factors associated with delayed and acute chemotherapy induced nausea and vomiting (CINV) are patients ethnicity, chemotherapy cycles and types, as well as pre and post antiemetic treatments used. As for the effect on QOL, delayed CINV has a higher negative effect on breast cancer patients QOL than acute CINV. Moreover it shows that there is a defect in the antiemetic treatment guideline which might be due to ethnic variation among the different races.en_US
dc.identifier.urihttp://hdl.handle.net/123456789/7686
dc.language.isoenen_US
dc.publisherUniversiti Sains Malaysiaen_US
dc.subjectChemotherapy Outcomeen_US
dc.subjectSolid Cancer Patientsen_US
dc.titleAssessment Of Chemotherapy Outcome And Adverse Event Management Among Solid Cancer Patients Of Penang Hospitalen_US
dc.typeThesisen_US
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