Design And Fabrication Of A 3d Printed Thyroid Phantom For Radiation Dosimetry
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Date
2018-03
Authors
Alssabbagh, Moayyad Mazen
Journal Title
Journal ISSN
Volume Title
Publisher
Universiti Sains Malaysia
Abstract
Estimation of internal and external radiation dose from SPECT/CT procedures
depends mainly on calculations of Medical Internal Radiation Dose (MIRD) methods.
Currently, there is no dynamic thyroid phantom with a precise geometrical shape which
can simulate the biokinetics of the radiopharmaceuticals in the thyroid. The goal of this
study was to design and fabricate a three-dimensional (3D) dynamic thyroid phantom for
dosimetry and image quality evaluation. Nine 3D printing materials were evaluated in
terms of elemental composition, mass attenuation coefficients, CT numbers and mass
density, where The Energy Dispersive X-ray Spectroscopy (SEM-EDS) machine, CT
scanner of two different CT modes (single-energy and dual-energy imaging) and online
version of the XCOM photon cross-section database were used. The results were
compared with the attenuation values of the thyroid, where polycarbonate (PC) material
shows a good match and can be used as a tissue-equivalent material for human thyroid to
3D print the thyroid phantom in this study. Hollow and solid thyroid phantoms were
designed using 3D Max software. Both thyroid models have two holes on each lobe for
installation of radiation dosimeters (i.e. thermoluminescence and optically stimulated
luminescence dosimeters). The infusion syringe pump was used to simulate the biokinetics
data of Tc-99m for internal dosimetry during SPECT/CT imaging. Seven percent of 370
MBq and 74 MBq were administered into the thyroid phantoms of adult and paediatric of
10 years old, respectively. The results were compared with International Commission on
Radiological Protection (ICRP) values and Organ Level Internal Dose
Assessment/Exponential Modelling (OLINDA/EXM) software.
Description
Keywords
Design and fabrication of a 3d printed , thyroid phantom for radiation dosimetry