Design And Fabrication Of A 3d Printed Thyroid Phantom For Radiation Dosimetry

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dc.contributor.authorAlssabbagh, Moayyad Mazen
dc.date.accessioned2019-04-17T01:33:13Z
dc.date.available2019-04-17T01:33:13Z
dc.date.issued2018-03
dc.description.abstractEstimation of internal and external radiation dose from SPECT/CT procedures depends mainly on calculations of Medical Internal Radiation Dose (MIRD) methods. Currently, there is no dynamic thyroid phantom with a precise geometrical shape which can simulate the biokinetics of the radiopharmaceuticals in the thyroid. The goal of this study was to design and fabricate a three-dimensional (3D) dynamic thyroid phantom for dosimetry and image quality evaluation. Nine 3D printing materials were evaluated in terms of elemental composition, mass attenuation coefficients, CT numbers and mass density, where The Energy Dispersive X-ray Spectroscopy (SEM-EDS) machine, CT scanner of two different CT modes (single-energy and dual-energy imaging) and online version of the XCOM photon cross-section database were used. The results were compared with the attenuation values of the thyroid, where polycarbonate (PC) material shows a good match and can be used as a tissue-equivalent material for human thyroid to 3D print the thyroid phantom in this study. Hollow and solid thyroid phantoms were designed using 3D Max software. Both thyroid models have two holes on each lobe for installation of radiation dosimeters (i.e. thermoluminescence and optically stimulated luminescence dosimeters). The infusion syringe pump was used to simulate the biokinetics data of Tc-99m for internal dosimetry during SPECT/CT imaging. Seven percent of 370 MBq and 74 MBq were administered into the thyroid phantoms of adult and paediatric of 10 years old, respectively. The results were compared with International Commission on Radiological Protection (ICRP) values and Organ Level Internal Dose Assessment/Exponential Modelling (OLINDA/EXM) software.en_US
dc.identifier.urihttp://hdl.handle.net/123456789/8022
dc.language.isoenen_US
dc.publisherUniversiti Sains Malaysiaen_US
dc.subjectDesign and fabrication of a 3d printeden_US
dc.subjectthyroid phantom for radiation dosimetryen_US
dc.titleDesign And Fabrication Of A 3d Printed Thyroid Phantom For Radiation Dosimetryen_US
dc.typeThesisen_US
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