Evaluation Of Treatment Outcomes, Factors Affecting Treatment Defaulting And Health Related Quality Of Life Of Newly Diagnosed Tuberculosis Patients In Yemen
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Date
2018-07
Authors
Jaber, Ammar Ali Saleh
Journal Title
Journal ISSN
Volume Title
Publisher
Universiti Sains Malaysia
Abstract
Despite the effectiveness of tuberculosis (TB) treatment, TB remains the most challenging infectious disease worldwide due to augmented trend of mortality and morbidity. In addition, in Yemen, TB consider as the 4th causes of death. Presentstudy is designed to evaluates TB among smear positive pulmonary tuberculosis (PTB) including treatment outcome, health related quality of life (HRQoL) and risk factors associated with TB defaulters. A prospective cohort study was designed. The study conducted in two high TB prevalent cities (Taiz and Al Hudaydah) of Yemen, between April 2014 and January 2016. Moreover, this study reported a lower success rate of 83% compare to WHO target of 85%. Likewise, the study report male gender (adjusted odds ratio [AOR]: 0.248, 95% CI: 0.239–0.874), illiterate (AOR: 2.294, 95% CI: 1.272–4.137), and comorbidity (AOR: 1.995, 95% CI: 1.108–3.590) were the risk factors associated with unsuccessful outcome. Moreover, living in rural areas (AOR: 1.97, 95% CI: 1.280-2.919),, having BMI ≥ 18.5 kg/m2 (AOR: 2.85, 95% CI: 2.194-3.652) were the risk factors related to prolonging sputum conversion during intensive phase. Moreover living in a rural area (adjusted odds ratio [AOR]: 2.358, 95% CI: 0.658–4.00), smoking (AOR: 0.054, 95% CI: 0.987–4.112), chewing khat (AOR: 2.615, 95% CI: 1.201–5.691), having a cough for >3 weeks at the start of treatment (AOR: 2.672, 95% CI: 1.053–6.782), and bilateral lesions during radiography (AOR: 2.134, 95% CI: 1.147–3.972) were a risk factor related to prolonging treatment duration (> 6 months).
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Keywords
Health related quality of life of newly diagnosed , tuberculosis patients in Yemen