Evaluation Of Treatment Outcomes, Factors Affecting Treatment Defaulting And Health Related Quality Of Life Of Newly Diagnosed Tuberculosis Patients In Yemen

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dc.contributor.authorJaber, Ammar Ali Saleh
dc.date.accessioned2019-04-19T07:22:33Z
dc.date.available2019-04-19T07:22:33Z
dc.date.issued2018-07
dc.description.abstractDespite the effectiveness of tuberculosis (TB) treatment, TB remains the most challenging infectious disease worldwide due to augmented trend of mortality and morbidity. In addition, in Yemen, TB consider as the 4th causes of death. Presentstudy is designed to evaluates TB among smear positive pulmonary tuberculosis (PTB) including treatment outcome, health related quality of life (HRQoL) and risk factors associated with TB defaulters. A prospective cohort study was designed. The study conducted in two high TB prevalent cities (Taiz and Al Hudaydah) of Yemen, between April 2014 and January 2016. Moreover, this study reported a lower success rate of 83% compare to WHO target of 85%. Likewise, the study report male gender (adjusted odds ratio [AOR]: 0.248, 95% CI: 0.239–0.874), illiterate (AOR: 2.294, 95% CI: 1.272–4.137), and comorbidity (AOR: 1.995, 95% CI: 1.108–3.590) were the risk factors associated with unsuccessful outcome. Moreover, living in rural areas (AOR: 1.97, 95% CI: 1.280-2.919),, having BMI ≥ 18.5 kg/m2 (AOR: 2.85, 95% CI: 2.194-3.652) were the risk factors related to prolonging sputum conversion during intensive phase. Moreover living in a rural area (adjusted odds ratio [AOR]: 2.358, 95% CI: 0.658–4.00), smoking (AOR: 0.054, 95% CI: 0.987–4.112), chewing khat (AOR: 2.615, 95% CI: 1.201–5.691), having a cough for >3 weeks at the start of treatment (AOR: 2.672, 95% CI: 1.053–6.782), and bilateral lesions during radiography (AOR: 2.134, 95% CI: 1.147–3.972) were a risk factor related to prolonging treatment duration (> 6 months).en_US
dc.identifier.urihttp://hdl.handle.net/123456789/8054
dc.language.isoenen_US
dc.publisherUniversiti Sains Malaysiaen_US
dc.subjectHealth related quality of life of newly diagnoseden_US
dc.subjecttuberculosis patients in Yemenen_US
dc.titleEvaluation Of Treatment Outcomes, Factors Affecting Treatment Defaulting And Health Related Quality Of Life Of Newly Diagnosed Tuberculosis Patients In Yemenen_US
dc.typeThesisen_US
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