OCULAR BIOMETRY, OPTIC NERVE HEAD PARAMETERS AND RETINAL NERVE FIBER LAYER THICKNESS IN SEVERE PRETERM MALAY CHILDREN
| dc.contributor.author | ALSHAARAWI, M.A. SALEM | |
| dc.date.accessioned | 2017-10-31T01:34:57Z | |
| dc.date.available | 2017-10-31T01:34:57Z | |
| dc.date.issued | 2012-03 | |
| dc.description.abstract | Introduction: Severe preterm delivery is defined as babies born at 32 weeks or less of gestation. The earlier the baby is born, the less likely he or she is to survive. Those who do survive are at a higher risk of lifelong health problems, of which the ophthalmic complications include retinopathy of prematurity, myopia, amblyobia, strabismus and optic nerve abnormalities. Objective : This study is to compare the ocular biometric parameters, optic nerve head parameters, and retinal nerve fiber layer thickness parameters between severe preterm and term Malay children aged 8-16 years old. Methodology: This comparison cross sectional study evaluated 64 patients, 32 patients were born less than 32 weeks of gestation and 32 patients were full term. All patients underwent thorough eye examination. Ocular biometry was performed using A- Scan ultrasound biometry, whilst optic nerve head parameters and retinal nerve fiber layer thickness were performed using Heidelberg Retinal Tomograph III. Results: There was a statistically shorter vitreous chamber depth between severe preterm group and term group, (p=0.04). However, there was no statistically significant difference of anterior chamber depth, lens thickness and axial length between severe preterm group and term group. The rim volume, cup shape measurement, height variation contour, and mean cup depth in severe preterm group were statistically increased compared to the term group and (p<0.05). However, the mean cup area, cup/disc, cup volume, mean rim area, cup/disc area, linear cup/disc area and maximum cup depth between severe preterm group and term group were not statistically significant (p>0.05). The mean nasal quadrant of retinal nerve fiber layer is significantly thinner in severe preterm children, whilst global retinal nerve fiber layer of nasal/superior quadrant and nasal/inferior quadrant are significantly thicker in severe preterm compared to term children. On the other hand, no significant differences have been reported in temporal quadrant, temporal/superior, and temporal/inferior quadrant between severe preterm group and term group (p>0.05). Conclusion: This study shows the vitreous chamber is significantly shorter in severe preterm children. The rim volume, cup volume, cup shape measurement, height variation contour and mean cup depth of optic nerve head are significantly different between severe preterm and term children. | en_US |
| dc.identifier.uri | http://hdl.handle.net/123456789/5177 | |
| dc.language.iso | en | en_US |
| dc.publisher | Pusat Pengajian Sains Perubatan Universiti Sains Malaysia | en_US |
| dc.subject | CLINICAL OPHTHALMOLOGY | en_US |
| dc.title | OCULAR BIOMETRY, OPTIC NERVE HEAD PARAMETERS AND RETINAL NERVE FIBER LAYER THICKNESS IN SEVERE PRETERM MALAY CHILDREN | en_US |
| dc.type | Thesis | en_US |
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