Small rna (sRNA) regulates extreme temperature adaptation of Geobacillus thermoleovorans isolated from a Malaysian hot spring.
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Date
2011-02
Authors
Hock Siew, Tan
Journal Title
Journal ISSN
Volume Title
Publisher
Universiti Sains Malaysia
Abstract
RNA kecil (sRNA) telah ditunjukkan memainkan peranan penting dalam pengawalan gen dalam eukariot (juga dikenali sebagai microRNA) dan prokariot. Dalam bakteria, sRNA mengawalatur pembentukan biofilem, penderian korum, kevirulenan dan gerak balas stres persekitaran. Antara pelbagai gerak balas stres, tindak balas kejutan suhu telah banyak dikaji dalam bakteria patogen dan extremofil.
Small RNA (sRNA) has been shown to play important gene regulatory roles in both eukaryotes (commonly known as microRNA) and prokaryotes. In bacteria, sRNAs regulate biofilm formation, quorum sensing, virulence, and environmental stress response. Of the various stress responses, the heat shock response has been extensively studied in many pathogenic bacteria and extremophiles.
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Keywords
Regulates , Temperature