Effects Of Tualang Honey On Reproductive System And Bone Properties In Ovariectomised Rats

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dc.contributor.authorMohamad Zaid, Siti Sarah
dc.date.accessioned2019-10-08T04:58:58Z
dc.date.available2019-10-08T04:58:58Z
dc.date.issued2011-05
dc.description.abstractHoney is a highly nutritional natural product that has been widely used in the folk medicine for a number of therapeutic purposes. In this study, Tualang honey was evaluated for its effectiveness in reducing postmenopausal changes in bilaterally ovariectomised rats. In study I (short term two weeks study), rats were randomly divided into five groups (n=7), which were the of sham control group (SHAM), ovariectomised control group (OVX), THL ovariectomised group (received 0.2 g/kg of Tualang honey), THM ovariectomised group (received 1.0 g/kg of Tualang honey) and THH ovariectomised group (received 2.0 g/kg of Tualang honey). Both SHAM and OVX groups received 0.5 ml vehicle treatment of distilled water. The treatment was given orally by gavage daily for two weeks. The reproductive organs (uterus and vagina) and tibia bone were subjected to histopathological examination while the serum was for hormonal assays. Administration of Tualang honey for two weeks to ovariectomised rats significantly increased the weight of the uterus and vagina (P<0.05), increased the thickness of vaginal epithelium and muscular layers (P<0.05), increased the thickness of uterine endometrium and myometrium layers (P<0.05), restored the thickness of trabecular tibia bone and suppressed the body weight (P<0.05) compared to OVX group.en_US
dc.identifier.urihttp://hdl.handle.net/123456789/8979
dc.language.isoenen_US
dc.publisherUniversiti Sains Malaysiaen_US
dc.subjectTualang Honeyen_US
dc.subjectReproductive Systemen_US
dc.titleEffects Of Tualang Honey On Reproductive System And Bone Properties In Ovariectomised Ratsen_US
dc.typeThesisen_US
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