The Preparation And Tile Dnug Release Of Polystyrene Microcapsul]S Containing Aqueous Soluble Drug
| dc.contributor.author | SELAMAT, ABDUL GHAPOR | |
| dc.date.accessioned | 2017-01-16T04:10:11Z | |
| dc.date.available | 2017-01-16T04:10:11Z | |
| dc.date.issued | 1981-02 | |
| dc.description.abstract | The Preparation and The ~)tudy of The Dr.lg Release ot ?olystyrene Hicrocapsules contai.."ling Aqueous Soluble Jrug. It consis~",: of t"v() 1.1~jor ~n.rts. Firstly was the study of The :::f.fect of ::)tirring on The Size}f The ?l"~crocapsules a.nd The Surf":lce Pore .:!urin.,,! preparation. Seco.ndly was The Study ot The Release Pattern of The :l!icroe2.psules with Different Pore Sizes. The detail Investl,r.atlon WAS done on polY'~tyre!le miC1'Ocapsules containing sodium salye,ylnte as the 2ctive In~dients.~s 'AaS prepared the method of evn?orating me~~lene chlori~e f~ an aqueous system. The shape of the woi"~f';psules WA.S spherlc:tl and .free nowir.g. The !)resenc~ of some tine bubbles and nome ,ockmark-li!:e holes vas ob~er-.red on the surface of ~~, capsules by the m1croscopic studies. the existence of holes was ohviously p,onfi~pd by studies on the release 9attern tram the dissolution test. The ,lot ot cumUlative percent~e of sodi~ s~licyl~te di~solved versus ti.":le was done. There were three '~~nses ot din::::olutlon cha~cter1st1c observed. Initially there was a ~~id rele~se followed by n ~du~l fall in the ~te ~d finally it plateaued of!. In eeneral the rate of dissolut~on incre~sed ~s the rate ~f 9tirrin~ Wns increased.In ~~other as:"lect the rate ot dissolution .llso increa.sed as the ~te of drJing ~las -f~ed on the:1Ore 91?C' Incr~ased. ':'he latter ""as probahly due to the 1ncre -' . of th~ micro~~n~ulcne | en_US |
| dc.identifier.uri | http://hdl.handle.net/123456789/3444 | |
| dc.subject | The Preparation And Tile Dnug Release Of | en_US |
| dc.subject | Polystyrene Microcapsul]S Containing Aqueous Soluble Drug | en_US |
| dc.title | The Preparation And Tile Dnug Release Of Polystyrene Microcapsul]S Containing Aqueous Soluble Drug | en_US |
| dc.type | Thesis | en_US |
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