A Hospital-Based Case-Control Study Of Factors Associated With Colorectal Cancer
| dc.contributor.author | Rosdi, Aminu Aisyahtun | |
| dc.date.accessioned | 2017-09-08T07:04:30Z | |
| dc.date.available | 2017-09-08T07:04:30Z | |
| dc.date.issued | 2016-08 | |
| dc.description.abstract | Colorectal cancer (CRC) was the second most common cancer in Malaysia after breast cancer. The incidence rates of CRC for both male and female had been reported increasing. This study was conducted to determine the associated factors of CRC in selected hospitals in Malaysia. A hospital-based case-control study of 128 cases and 128 controls was carried out by using a validated questionnaire. Participants who fulfilled the inclusion and exclusion criteria were included as the case and control groups accordingly. Multiple logistic regression was used for data analysis. The mean age of CRC was 59.84 years old (standard deviation 11.20). Majority of CRC was males (60.9%) and Malay race (57.8%). The significant factors associated with CRC were age equal and more than 55 years old [Adjusted Odds Ratio (AOR): 4.54; 95% confidence interval (CI): 2.45-8.40; p value <0.001], Chinese ethnicity [AOR: 6.67; 95% CI: 2.01-22.13; p value = 0.002], family history of CRC [AOR: 11.26; 95% CI: 3.02-41.94; p value <0.001], history of polyps [AOR: 5.45; 95% CI: 1.94-15.28; p value <0.001], and ever smoker [AOR: 3.40; 95% CI: 1.63-7.10; p value <0.001]. As a conclusion, factors significantly associated with CRC are older age, chinese ethnicity, family history of CRC, history of polyps and ever smoked. These factors could be used as a reference to guide the people and Ministry of Health on risk factors to get CRC, adopting a healthy lifestyle in order to decrease the incidence of CRC in Malaysia. | en_US |
| dc.identifier.uri | http://hdl.handle.net/123456789/4548 | |
| dc.language.iso | en | en_US |
| dc.publisher | Universiti Sains Malaysia | en_US |
| dc.subject | Colorectal cancer was the second | en_US |
| dc.subject | most common cancer in Malaysia. | en_US |
| dc.title | A Hospital-Based Case-Control Study Of Factors Associated With Colorectal Cancer | en_US |
| dc.type | Thesis | en_US |
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