Kesan minyak esensial citrus SPP ke atas sistem kardiovaskular tikus serta kesan antiresah dan antidepresi pada mencit
| dc.contributor.author | Che Awang, Che Rugayah | |
| dc.date.accessioned | 2015-07-30T03:51:24Z | |
| dc.date.available | 2015-07-30T03:51:24Z | |
| dc.date.issued | 2007 | |
| dc.description.abstract | This study attempts to look at the effects of three essential oils from members of the Citrus family of plants on the cardiovascular system of the rats and to look at possible antianxiety and antidepressive effects of these oils. It's balmy smell suggest that these essential oils could produce relaxation possibly via its action on the central nervous system and subsequently may influence indirectly the cardiovascular system. The study focused on the effects of essential oils of Citrus spp on the blood pressure and heart rate of rats (the effect of direct aroma test via the nasal passage), and the antianxiety and antidepressive effects of these essential oils in mice. The results obtained may be correlated to the effects seen on human emotion (Elevated Plus-maze test and Behavioral Despair or Forced Swimming test). Essential oils of 3 members of the Citrus genus from the Rutaceae family were used. Specifically they are the Citrus hystrix, D. C. (wild lime or 'limau purut'), Citrus microcarpa (musk lime or 'limau kasturi') and Citrus aurantifolia (common lime or 'limau nipis'). These plants are traditionally used as medicaments by Malays, perhaps due to its strong and characteristic smell. Intranasal C. hystrix shows significant hypotensive (p < 0.05) on the blood pressure (systolic and dystolic) with sustained hypotensive for 5.30 ± 5.5 minutes, but for the heart rate of the rats, it is not significantly (p > 0.05) different. Results from our experiment showed the smelling of essential oils (0.1 ml) of C. hystrix and C. microcarpa conffered antianxiety and C. aurantifolia has antidepressive properties. The thesis describes the effects of essential oils of the three Citrus spp and suggestions as to the possible mode of action of these oils on the cardiovascular system and the central nerve system. | en_US |
| dc.identifier.uri | http://hdl.handle.net/123456789/976 | |
| dc.language.iso | other | en_US |
| dc.subject | Esensial Citrus SPP | en_US |
| dc.subject | Kardiovaskular tikus | en_US |
| dc.subject | Antidepresi | en_US |
| dc.title | Kesan minyak esensial citrus SPP ke atas sistem kardiovaskular tikus serta kesan antiresah dan antidepresi pada mencit | en_US |
| dc.type | Thesis | en_US |
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