57th. Annual National Conference of Indian Society of Anaestbesiologists 2009 Chennai, India 26 - 30 Dis ember 2009.
| dc.contributor.author | Gnandev, Pbutane | |
| dc.date.accessioned | 2022-09-12T07:25:37Z | |
| dc.date.available | 2022-09-12T07:25:37Z | |
| dc.date.issued | 2009 | |
| dc.description.abstract | Background end goals of study. to evaluate the eflicacy,safety,tolerability & side effect between of pregabalin, gabapentin and topiramate in chronic pain management Methods: Prospective, double blind,randomized controlled trial of 12 weeks duration comparing pregabalin, gabapentin & topiramate. Study was conducted on patient with chronic pain clinic at LLRH, Kanpur. Participants were 120 patients with chronic pain. Tha primary outcome was difference between pregabalin, gabapentine & topiramate in chronic pain, as measured by the mean VAS score computed over weekly of each treatment period.Secondary outcomes were changes in mood, quality of life & psychomotor functions.Side effects were measured by questionnaire. Patient received a maximum dally dose of 600 mg gabapentine or 400 mg pregabalin or 1 00 mg topiramate along with 300 mg aceclofenac Results: Mean baselineVAS was 69.6 mm (29.4-95.2) on a scale of 0-100mm.120 patients were included in the available case analysis & 30 patients in the per protocol analysis. The mean score was 6mm longer for gabapentine than for pregabalin & topiramate in the available case analysis & 5.6 mm in the per protocol analysis. Cone/us/on: Gabapentine provided better pain relief than the pregabalin & topiramate & had slightly fewer side effects, well tolerable, although no major adverse events occur for either drug. | en_US |
| dc.identifier.uri | http://hdl.handle.net/123456789/16029 | |
| dc.publisher | Pusat Pengajian Sains Perubatan | en_US |
| dc.title | 57th. Annual National Conference of Indian Society of Anaestbesiologists 2009 Chennai, India 26 - 30 Dis ember 2009. | en_US |
| dc.type | Other | en_US |
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