The Effects of Various Surfactants and Penetrants on the Percutendous Absorption of Dermatological Products
| dc.contributor.author | YUSOFF, ABDUL AZIZ | |
| dc.date.accessioned | 2016-07-18T02:44:31Z | |
| dc.date.available | 2016-07-18T02:44:31Z | |
| dc.date.issued | 1981-02 | |
| dc.description.abstract | In vitro release of salicylic acid from oint~ent bases \';a3 inVC3tie3. ted I)":; a di ffus:-:;ion tec hnique er.r9loying Ghicken porch as a Skin model. The ointmant bases used were TIoolfat (anhydrous), ~hite soft paraffin, emulsion ~ type, and )clyethylene Glycol. 10 percent of salicylic acid waa incorporat~d into each of the ointments prc]ared. T~o surfactants sodium lauryl sulphate and dioctyl sodium sulfosuccinate and two penetrants _ cholesterol and '~imethylsulfo~ide (DMSO) were used to study their effec~s on the release pattern of salic:rlic acid from the ointments. 10 ~e!ยท:;cr:.t of each ',vere incor)ora ::2(~ into the oint:.lsnts. soc.iu:!l lauryl sulphate ','Tas found to in::r r:3se the release 0f salicylic acid from e~ul~!0n - ty~e oint- T:1ent ba.-:;e. Dioc tyl sodiUl:l sulfosuccina te and Cholestarol ~ere found to increase the release from emulsion _ type and polyethylene Sly~ol bases. ~hilst DM30 facilitated the relca~c rr0~ e~ulsion - ty~e and ~hitc soft Dara:rin oases. | en_US |
| dc.identifier.uri | http://hdl.handle.net/123456789/2253 | |
| dc.subject | The Effects of Various Surfactants and Penetrants on the Percutendous Absorption | en_US |
| dc.subject | of Dermatological Products | en_US |
| dc.title | The Effects of Various Surfactants and Penetrants on the Percutendous Absorption of Dermatological Products | en_US |
| dc.type | Thesis | en_US |
Files
License bundle
1 - 1 of 1
Loading...
- Name:
- license.txt
- Size:
- 1.71 KB
- Format:
- Item-specific license agreed upon to submission
- Description: