Institut Perubatan & Pergigian Termaju - Tesis

Browse

Now showing 1 - 1 of 1

Antibacterial Activity And Biocompatibility Of Polyphenol Crosslinked Zno-Cuo Nanocomposite Hydrogel As A Wound Healing Agent
(2025-07)
Ramtan, Gadaime Nasrin K
Treating exuding open skin wounds present significant challenges, primarily due to the risk of bacterial infections, particularly those caused by antibiotic-resistant strains, which can impede the healing process. Traditional wound dressings are insufficient for creating an optimal healing environment, as traditional dressings fail to effectively regulate the complex wound microenvironment, which is characterised by challenges such as excessive exudate, and bacterial contamination. The present study aimed to develop and characterize a multifunctional wound dressing containing polyphenol and nanocomposite components, with evaluations encompassing structural and chemical properties, antibacterial activities, cytocompatibility, hemocompatibility, and wound-healing potential. The current study was divided into polyphenol / ZnO-CuO nanocomposite embedded in PEG hydrogel (CPZCH-X) preparation with the structural and chemical properties analyses